Ivermectin 70288-86-7

1.We supply ivermectin 2.White crystalline powder 3.High qulity competitive price 4.Prompt delivery 5.USP/BP

 

 

Description

 

Ivermectin (22,23-dihydroavermectin B1a + 22,23-dihydroavermectin B1b) is a broad-spectrum antiparasitic avermectin medicine.

 

 

 

Analyse

 

Product	Ivermectin
CAS	70288-86-7
Molecular formular	C95H146O28
Molecular  weight	1736.15894
Appearance	White crystalline powder
Melting point	154.5~157°C
Completeness of solution	Conform
Water-solubility	0.12 g/100 mL (25°C)
Grade	Medicine grade
Related Substance	< 0.5%
Heavy Metal	< 20ppm
Loss on drying	0.08%
Residue on ignition	0.05%
Assay	99.0%

Sealed tightly and stored away from light in a  cool and dry place.

Uses

Ivermectin is a broad-spectrum antiparasitic agent.

Helminth

It is traditionally used against worms.

It is mainly used in humans in the treatment of onchocerciasis, but is also effective against other worm infestations (such as strongyloidiasis, ascariasis, trichuriasis, filariasis, enterobiasis and some epidermal parasitic skin diseases (EPSDs), including scabies.

Ivermectin, under the brand name Mectizan, is currently being used to help eliminate river blindness (onchocerciasis) in the Americas, and to stop transmission of lymphatic filariasis and onchocerciasis around the world.Currently, large amounts of ivermectin are donated by Merck to fight river blindness in countries unable to afford the drug.The disease is endemic in 30 African countries, six Latin American countries, and Yemen, according to studies conducted by the World Health Organization.The drug rapidly kills microfilariae, but not the adult worms. A single oral dose of ivermectin, taken annually for the 10-15 year life span of the adult worms, is all that is needed to protect the individual from onchocerciasis.

Arthropod

More recent evidence supports its off-label use against arthropods:

Mites such as scabies.It is usually limited to cases that prove resistant to topical treatments and/or which present in an advanced state (such as Norwegian scabies).

Lice. Ivermectin lotion (0.5%) is FDA approved for patients 6 months of age and older.

Veterinary use

Ivermectin is also used in veterinary medicine. It is sometimes administered in combination with other medications to treat a broad spectrum of animal parasites. Some dog breeds (especially the Rough Collie, the Smooth Collie, the Shetland Sheepdog and the Australian Shepherd), though, have a high incidence of a certain mutation within the MDR1 gene; affected animals are particularly sensitive to the toxic effects of ivermectin.[14] Clinical evidence suggests that kittens are susceptible to ivermectin toxicity.[15] A 0.01% ivermectin topical preparation for treating ear mites in cats (Acarexx) is available.

Ivermectin is sometimes used as an acaricide in reptiles, both by injection and as a diluted spray. While this works well in some cases, care must be taken, as several species of reptile are very sensitive to ivermectin. Use in turtles is particularly contraindicated.

Contact information

Gary Ren

Zhengzhou Debao Fine Chemical co., ltd

Address:Room 305, Building 4, Jincheng International, Jingsan Road, Zhengzhou, China.

Tel: 0086 371 69123138

Fax: 0086 371 69123168

Mob:86 15038002977

http://chinadebaos.en.alibaba.com/

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Ivermectin 70288-86-7